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1

Imatinib mesylate improves insulin sensitivity and glucose disposal rates in rats fed a high-fat diet

Hägerkvist, Robert, Jansson, Leif, Welsh, Nils

Journal:

Clinical Science

Year:

2008

Language:

english

File:

PDF, 414 KB

english, 2008

2

Decreased cell replication and polyamine content in insulin-producing cells after exposure to human interleukin 1β

Stellan Sandler, Klaus Bendtzen, Décio L. Eizirik, Åke Sjöhlm, Nils Welsh

Journal:

Immunology Letters

Year:

1989

Language:

english

File:

PDF, 539 KB

english, 1989

3

Imatinib mesylate (Gleevec) protects against streptozotocin-induced diabetes and islet cell death in vitro

Robert Hägerkvist, Natalia Makeeva, Stephen Elliman, Nils Welsh

Journal:

Cell Biology International

Year:

2006

Language:

english

File:

PDF, 298 KB

english, 2006

4

Islet expression of perforin, Fas/Apo-1 and interleukin-1 converting enzyme (ICE) in non-obese diabetic (NOD) mice

Erik Ingelsson, Johan Saldeen, Nils Welsh

Journal:

Immunology Letters

Year:

1998

Language:

english

File:

PDF, 128 KB

english, 1998

5

Detailed transcriptome atlas of the pancreatic beta cell

Burak Kutlu, David Burdick, David Baxter, Joanne Rasschaert, Daisy Flamez, Decio L Eizirik, Nils Welsh, Nathan Goodman, Leroy Hood

Journal:

BMC Medical Genomics

Year:

2009

Language:

english

File:

PDF, 759 KB

english, 2009

6

Promoting islet cell function after transplantation

Arne Andersson, Per-Ola Carlsson, Carina Carlsson, Richard Olsson, Astrid Nordin, Magnus Johansson, Fredrik Palm, Björn Tyrberg, Örjan Källskog, Linda Tillmar, Nils Welsh, Göran Mattsson, Leif Jansson

Journal:

Cell Biochemistry and Biophysics

Year:

2004

Language:

english

File:

PDF, 1.07 MB

english, 2004

7

Decrease in insulin-containing secretory granules and mitochondrial gene expression in mouse pancreatic islets maintained in culture following streptozotocin exposure

Jorge E. Moreira, Arthur R. Hand, L. A. Håkan Borg, Stellan Sandler, Michael Welsh, Nils Welsh, Décio L. Eizirik

Journal:

Virchows Archiv B Cell Pathology Zell-pathologie

Year:

1991

Language:

english

File:

PDF, 4.00 MB

english, 1991

8

Metabolism and β-cell function of rat pancreatic islets exposed to human interleukin-1β in the presence of a high glucose concentration

Stellan Sandler, Klaus Bendtzen, Décio L. Eizirik, Eva Strandell, Michael Welsh, Nils Welsh

Journal:

Immunology Letters

Year:

1990

Language:

english

File:

PDF, 528 KB

english, 1990

9

Apoptosis in Embryos of Diabetic Rats

Henrik Forsberg, Ulf J. Eriksson, Nils Welsh

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

1998

Language:

english

File:

PDF, 991 KB

english, 1998

10

siRNA Produced by Recombinant Dicer Mediates Efficient Gene Silencing in Islet Cells

ROBERT HÄGERKVIST, DARIUSH MOKHTARI, JASON W. MYERS, ANDERS TENGHOLM, NILS WELSH

Journal:

Annals of the New York Academy of Sciences

Year:

2005

Language:

english

File:

PDF, 5.43 MB

english, 2005

11

Nicotinamide- and caspase-mediated inhibition of poly(ADP-ribose) polymerase are associated with p53-independent cell cycle (G2) arrest and apoptosis

Johan Saldeen, Linda Tillmar, Ella Karlsson, Nils Welsh

Journal:

Molecular and Cellular Biochemistry

Year:

2003

Language:

english

File:

PDF, 135 KB

english, 2003

12

Glucose-induced binding of the polypyrimidine tract-binding protein (PTB) to the 3′-untranslated region of the insulin mRNA (ins-PRS) is inhibited by rapamycin

Linda Tillmar, Nils Welsh

Journal:

Molecular and Cellular Biochemistry

Year:

2004

Language:

english

File:

PDF, 83 KB

english, 2004

13

Promoting islet cell function after transplantation

Arne Andersson, Per-Ola Carlsson, Carina Carlsson, Richard Olsson, Astrid Nordin, Magnus Johansson, Fredrik Palm, Björn Tyrberg, Örjan Källskog, Linda Tillmar, Nils Welsh, Göran Mattsson, Leif Jansson

Journal:

Cell Biochemistry and Biophysics

Year:

2004

Language:

english

File:

PDF, 224 KB

english, 2004

14

A role for tyrosine kinase activation in interleukin-1β induced nitric oxide production in the insulin producing cell line RINm-5F

Journal:

Bioscience Reports

Year:

1994

Language:

english

File:

PDF, 475 KB

english, 1994

15

Possible role of an ischemic preconditioning-like response mechanism in KATP channel opener-mediated protection against streptozotocin-induced suppression of rat pancreatic islet function

Stellan Sandler, Annika K. Andersson, Jenny Larsson, Natalia Makeeva, Therese Olsen, Per O.G. Arkhammar, John Bondo Hansen, F. Anders Karlsson, Nils Welsh

Journal:

Biochemical Pharmacology

Year:

2008

Language:

english

File:

PDF, 663 KB

english, 2008

16

Consequences of Shb and c-Abl interactions for cell death in response to various stress stimuli

Robert Hägerkvist, Dariush Mokhtari, Cecilia Lindholm, Filip Farnebo, Gustavo Mostoslavsky, Richard C. Mulligan, Nils Welsh, Michael Welsh

Journal:

Experimental Cell Research

Year:

2007

Language:

english

File:

PDF, 755 KB

english, 2007

17

Role of p38 mitogen-activated protein kinase (p38 MAPK) in cytokine-induced rat islet cell apoptosis

Johan Saldeen, John C Lee, Nils Welsh

Journal:

Biochemical Pharmacology

Year:

2001

Language:

english

File:

PDF, 545 KB

english, 2001

18

S-METHYL-L-THIOCITRULLINE COUNTERACTS INTERLEUKIN 1β-INDUCED SUPPRESSION OF PANCREATIC ISLET FUNCTION IN VITRO, BUT DOES NOT PROTECT AGAINST MULTIPLE LOW-DOSE STREPTOZOTOCIN-INDUCED DIABETES IN VIVO

Johnny Sternesjö, Nils Welsh, Stellan Sandler

Journal:

Year:

1997

Language:

english

File:

PDF, 192 KB

english, 1997

19

LIPOSOME-MEDIATED TRANSFER OF IL-1 RECEPTOR ANTAGONIST GENE TO DISPERSED ISLET CELLS DOES NOT PREVENT RECURRENCE OF DISEASE IN SYNGENEICALLY TRANSPLANTED NOD MICE

Johan Saldeen, Stellan Sandler, Klaus Bendtzen, Nils Welsh

Journal:

Year:

2000

Language:

english

File:

PDF, 92 KB

english, 2000

20

Interleukin-1β induces the expression of an isoform of nitric oxide synthase in insulin-producing cells, which is similar to that observed in activated macrophages

Décio L. Eizirik, Enrico Cagliero, Andres Björklund, Nils Welsh

Journal:

Year:

1992

Language:

english

File:

PDF, 286 KB

english, 1992

21

Interleukin-1 -induced expression of nitric oxide synthase in insulin-producing cells is preceded by c-fos induction and depends on gene transcription and protein synthesis

Décio L. Eizirik, Andreas Björklund, Nils Welsh

Journal:

Year:

1993

Language:

english

File:

PDF, 548 KB

english, 1993

22

Succinic acid monomethyl ester protects rat pancreatic islet secretory potential against interleukin-1β (IL-1β) without affecting glutamate decarboxylase expression or nitric oxide production

Décio L. Eizirik, Nils Welsh, Audrey Niemann, Licio A. Velloso, Willy J. Malaisse

Journal:

Year:

1994

Language:

english

File:

PDF, 648 KB

english, 1994

23

Cytokines activate the nuclear factor κB (NF-κB) and induce nitric oxide production in human pancreatic islets

Malin Flodströma, Nils Welsh, Décio L. Eizirik

Journal:

Year:

1996

Language:

english

File:

PDF, 538 KB

english, 1996

24

Interleukin-1β-induced stimulation of insulin release in mouse pancreatic islets is related to diacylglycerol production and protein kinase C activation

Décio L. Eizirik, Stellan Sandler, Nils Welsh, Lisa Juntti-Berggren, Per-Olof Berggren

Journal:

Molecular and Cellular Endocrinology

Year:

1995

Language:

english

File:

PDF, 932 KB

english, 1995

25

Increased expression of polypyrimidine tract binding protein results in higher insulin mRNA levels

Rikard G. Fred, Nils Welsh

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 723 KB

english, 2005

26

Increased Hsp70 expression attenuates cytokine-induced cell death in islets of Langerhans from Shb knockout mice

Dariush Mokhtari, Björn Åkerblom, Ilir Mehmeti, Xuan Wang, Nina S. Funa, Johan Olerud, Sigurd Lenzen, Nils Welsh, Michael Welsh

Journal:

Biochemical and Biophysical Research Communications

Year:

2009

Language:

english

File:

PDF, 318 KB

english, 2009

27

The human insulin mRNA is partly translated via a cap- and eIF4A-independent mechanism

Rikard G. Fred, Monica Sandberg, Jerry Pelletier, Nils Welsh

Journal:

Biochemical and Biophysical Research Communications

Year:

2011

Language:

english

File:

PDF, 482 KB

english, 2011

28

Cytokine-induced human islet cell death in vitro correlates with a persistently high phosphorylation of STAT-1, but not with NF-κB activation

Henrietta Hindlycke, Tao Lu, Nils Welsh

Journal:

Biochemical and Biophysical Research Communications

Year:

2012

Language:

english

File:

PDF, 532 KB

english, 2012

29

The importance of RNA binding proteins in preproinsulin mRNA stability

Rikard G. Fred, Nils Welsh

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 268 KB

english, 2009

30

Interleukin-1β induces nitric oxide production and inhibits the activity of aconitase without decreasing glucose oxidation rates in isolated mouse pancreatic islets

Nils Welsh, Stellan Sandler

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 465 KB

english, 1992

31

Cytokine-induced apoptosis and necrosis are preceded by disruption of the mitochondrial membrane potential (Δψm) in pancreatic RINm5F cells: prevention by Bcl-2

Andreea Barbu, Nils Welsh, Johan Saldeen

Journal:

Molecular and Cellular Endocrinology

Year:

2002

Language:

english

File:

PDF, 198 KB

english, 2002

32

Nicotinamide-induced apoptosis in insulin producing cells is associated with cleavage of poly(ADP-ribose) polymerase

Johan Saldeen, Nils Welsh

Journal:

Molecular and Cellular Endocrinology

Year:

1998

Language:

english

File:

PDF, 598 KB

english, 1998

33

Lipofection of Insulin-Producing RINm5F Cells: Methodological Improvements

Barbu, Andreea, Welsh, Nils

Journal:

Journal of Liposome Research

Year:

2007

Language:

english

File:

PDF, 1.74 MB

english, 2007

34

Interleukin-1β induces the expression of HSP70, heme oxygenase and Mn-SOD in FACS-purified rat islet β-cells, but not in α-cells

Eva Strandell, Karsten Buschard, Johan Saldeen, Nils Welsh

Journal:

Immunology Letters

Year:

1995

Language:

english

File:

PDF, 436 KB

english, 1995

35

Regulation of RNA metabolism in relation to insulin production and oxidative metabolism in mouse pancreatic islets in vitro

Nils Welsh, Stellan Sandler, Michael Welsh, Claes Hellerström

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

1986

Language:

english

File:

PDF, 880 KB

english, 1986

36

In Vitro Restoration of Insulin Production in Islets from Adult Rats Treated Neonatally with Streptozotocin

WELSH, NILS, HELLERSTRÖM, CLAES

Journal:

Year:

1990

Language:

english

File:

PDF, 916 KB

english, 1990

37

Temporal profiling of cytokine-induced genes in pancreatic β-cells by meta-analysis and network inference

Lopes, Miguel, Kutlu, Burak, Miani, Michela, Bang-Berthelsen, Claus H., Størling, Joachim, Pociot, Flemming, Goodman, Nathan, Hood, Lee, Welsh, Nils, Bontempi, Gianluca, Eizirik, Decio L.

Journal:

Year:

2014

Language:

english

File:

PDF, 1.30 MB

english, 2014

38

Stimulation of Pancreatic Islet Beta-Cell Replication by Oncogenes

Michael Welsh, Nils Welsh, Thomas Nilsson, Per Arkhammar, R. Blake Pepinsky, Donald F. Steiner and Per-Olof Berggren

Journal:

Proceedings of the National Academy of Sciences

Year:

1988

Language:

english

File:

PDF, 947 KB

english, 1988

39

Aberrant Expression of Receptors for Platelet-Derived Growth Factor in an Anaplastic Thyroid Carcinoma Cell Line

Nils-Erik Heldin, Bengt Gustavsson, Lena Claesson-Welsh, Annet Hammacher, Joachim Mark, Carl-Henrik Heldin and Bengt Westermark

Journal:

Proceedings of the National Academy of Sciences

Year:

1988

Language:

english

File:

PDF, 1.11 MB

english, 1988

40

Failure of Glucose to Elicit a Normal Secretory Response in Fetal Pancreatic Beta Cells Results from Glucose Insensitivity of the ATP-Regulated K+Channels

Patrik Rorsman, Per Arkhammar, Krister Bokvist, Claes Hellerstrom, Thomas Nilsson, Michael Welsh, Nils Welsh and Per-Olof Berggren

Journal:

Proceedings of the National Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 1.23 MB

english, 1989

41

Interleukin-1β Depletes Insulin Messenger Ribonucleic Acid and Increases the Heat Shock Protein hsp70 in Mouse Pancreatic Islets Without Impairing the Glucose Metabolism*

EIZIRIK, DfiCIO L., WELSH, MICHAEL, STRANDELL, EVA, WELSH, NILS, SANDLER, STELLAN

Journal:

Year:

1990

Language:

english

File:

PDF, 1.21 MB

english, 1990

42

Interleukin-1β Increases the Biosynthesis of the Heat Shock Protein hsp70 and Selectively Decreases the Biosynthesis of five Proteins in rat Pancreatic Islets

Welsh, Nils, Welsh, Michael, Lindquist, Susan, Eizirik, Deacio L., Bendtzen, Klaus, Sandler, Stellan

Journal:

Year:

1991

Language:

english

File:

PDF, 1.85 MB

english, 1991

43

The Acid Sphingomyelinase Inhibitor SR33557 Counteracts TNF-α-Mediated Potentiation of IL-1β-Induced NF-κB Activation in the Insulin-Producing Cell Line RINm5F

Saldeen, Johan, Jaffrezou, Jean-Pierre, Welsh, Nils

Journal:

Year:

2000

Language:

english

File:

PDF, 1.18 MB

english, 2000

44

Biochemical and Molecular Actions of Interleukin-1 on Pancreatic β-Cells

Sandler, Stellan, Eizirik, Décio L., Svensson, Carina, Strandell, Eva, Welsh, Michael, Welsh, Nils

Journal:

Year:

1991

Language:

english

File:

PDF, 1.38 MB

english, 1991

45

Bcl-2 maintains the mitochondrial membrane potential, but fails to affect production of reactive oxygen species and endoplasmic reticulum stress, in sodium palmitate-induced β-cell death

Wang, Xuan, Welsh, Nils

Journal:

Upsala Journal of Medical Sciences

Year:

2014

Language:

english

File:

PDF, 713 KB

english, 2014

46

The H1-Receptor Antagonist Cetirizine Protects Partially Against Cytokine- and Hydrogen Peroxide–Induced β-TC6 Cell Death In Vitro

Anvari, Ebrahim, Fred, Rikard G., Welsh, Nils

Journal:

Year:

2014

Language:

english

File:

PDF, 1.47 MB

english, 2014

47

Does the small tyrosine kinase inhibitor imatinib mesylate counteract diabetes by affecting pancreatic islet amyloidosis and fibrosis?

Journal:

Expert Opinion on Investigational Drugs

Year:

2012

Language:

english

File:

PDF, 384 KB

english, 2012

48

The H1-receptor antagonist cetirizine ameliorates high-fat diet-induced glucose intolerance in male C57BL/6 mice, but not diabetes outcome in female non-obese diabetic (NOD) mice

Anvari, Ebrahim, Wang, Xuan, Sandler, Stellan, Welsh, Nils

Journal:

Upsala Journal of Medical Sciences

Year:

2015

Language:

english

File:

PDF, 499 KB

english, 2015

49

Imatinib mesylate stimulates low-density lipoprotein receptor-related protein 1-mediated ERK phosphorylation in insulin-producing cells

Fred, Rikard G., Boddeti, Santosh Kumar, Lundberg, Marcus, Welsh, Nils

Journal:

Clinical Science

Year:

2015

Language:

english

File:

PDF, 808 KB

english, 2015

50

The Role of PTB in Insulin mRNA Stability Control

G. Fred, Rickard, Tillmar, Linda, Welsh, Nils

Journal:

Current Diabetes Reviews

Year:

2006

Language:

english

File:

PDF, 35 KB

english, 2006